We've had this issue with Adobe Reader XI, and Outlook 2010. What happens is when a PDF attachment is opened inm Outlook, Outlook will freeze and crash.
If the user right click the PDF attachment in Outlook and chooses either option of "Preview" or "Save As", the attachments opens fine.
What makes this problem especially hard to solve is that it has not been replicated across all users on the network, just a handful.
Any idea how to troubleshoot...
Regards,